Biography of Rachel Elzes

about-me

Rachel Elzes

- PhD -

Location: Carré 4.326
Phone Number: +31 (0)53 489 3027
E-mail Address: m.r.elzes@utwente.nl

Research Topic: Size-controlled nanogels

The size of nanoparticles is known to dramatically affect biological processes such as cellular uptake, tissue/tumor penetration and immune response. In particular, particles smaller than 100 nm show improved tissue penetration. This project focuses on the preparation of size-controlled, sub-100 nm nanogels, for applications such as drug delivery, gene therapy and medical imaging.

Education:

2014-present

PhD-student
University of Twente, the Netherlands
Project: Development of PET-MRI Dual-Probe Nanoparticles for Early Diagnosis of Prostate Cancer, group of dr. Jos Paulusse (Department of Biomaterials Science and Technology)

2012-2014

Double degree Master of Science (MSc), Chemical Engineering & Biomedical Engineering, graduated cum laude
University of Twente, the Netherlands
Thesis: Bioreducible Poly(Amido Amine)-based Architectures for Gene Therapy, group of dr. Jos Paulusse (Department of Biomaterials Science and Technology)

2011-2012

Internship
University of Utrecht, the Netherlands
Project: Synthesis of bromomethyl sulfoxides as potential cysteine protease inhibitors, group of Prof. Robert Liskamp (Medicinal Chemistry)

2008-2011

Bachelor of Science (BSc), Scheikunde
University of Utrecht, the Netherlands
Thesis: The Dehydration of Alcohols To Alkenes Using Phosphino Rhenium (V) Complexes, group of Prof. Bert Klein Gebbink (Organic Chemistry & Catalysis)

 


Publications of Rachel Elzes

Jump to: 2018 | 2017 | 2016

2018

M.R. Elzes, G. Si, J.F.J. Engbersen and J.M.J. Paulusse, Thiourea-Functional Bioreducible Poly(amido amine)s in Gene Delivery. In: M. Ilies and K. Sakurai (Ed.), Targeted Nanosystems for Therapeutic Applications: New Concepts, Dynamic Properties, Efficiency, and Toxicity. Chapter 5, 2018, ACS Publications, Washington, 93–117.

G. Si, M.R. Elzes, J.F.J. Engbersen and J.M.J. Paulusse, Modular Synthesis of Bioreducible Gene Vectors through Polyaddition of N,N′-Dimethylcystamine and Diglycidyl Ethers, Polymers, 2018, 10, 687.

2017